DDG filter computes binding score for the complex
(threshold=0 only allows complexes with negative binding score)
(repeats=3 calculates binding score three times and returns average)
(repack=1 repack complex in both bound and unbound states to calculate binding score)
SASA filter computes interface solvent-accessible surface area
(threshold=800 only allows complexes with greater than 800 Å^2
as per Janin et al., Quarterly Reviews of Biophysics, 2008)
Designs and repacks interface residues of chain 1 and repacks interface residues of chain 2
Reads command line options
Runs local refinement stage of full atom docking
Runs protein interface design
Runs full atom side-chain and backbone minimization
Runs movers and filters in this order